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The role of HEPES|7365-45-9 in popular skincare products 2020-04-29 15:50:52

In recent years, as consumers pay more attention to Ingredients for skincare products and brands' emphasis on ingredient promotion, more and more skin care additives have begun to enter the public eye. Such as hyaluronic acid, nicotinamide, HEPES(CAS:7365-45-9), etc.Today I will talk to you about HEPES, a common skincare ingredient.

Peopel who pay attention to the L'Oreal brand should be familiar with HEPES. Many of L'Oreal's products have HEPES in their ingredients. Such as L'Oreal Revitalift Crystal Pire Centella Micro .essence Water , Revitalift Intensive Repairing Essence , Youth Code Ferment Pre.essence , etc. In addition, Skincare products from other famous brands also have HEPES,for example,YSL Night Queen's Essence, KIEHL'S Night Rejuvenating Cream, Lancome's Moisturizing Soothing Night Cream  , etc. So what exactly is HEPES and what role does it play in skincare?




HEPES ,a zwitterionic buffer, is widely used in cell culture medium, IVD kits and other fields. It can control a constant pH range for a long time and is non-toxic to cells, it can also be used as a common skin care additive.

The functions of HEPES inskin careproducetsare as follows:

First of all,as anew generation pH regulator,plays a role in maintaining the quality of cosmetics.

Because the range of pH value of HEPES regulating solution is 6.8 to 8.2, which is especially suitable for pH adjustment under physiological conditions.So HEPES plays an important role in skin care products by balancing the properties of its acidic counterpart.

Secondly, it can promote the absorption of effective ingredients in skin care.

As we all know, skin care can only be fully absorbed to play the effect of skin care. If the nutrients in skin care can not be fully absorbed, it may cause "skin oxidation" due to the excessive nutrition of the epidermis, resulting in premature aging of the skin, skin infection. Now it is HEPES 'turn.


HEPES is a safe and efficient skin care enhancer that can promote the absorption of nutrients in cosmetics without entering the subcutaneous tissues and the circulation in the human body. It not only overcomes the skin irritation caused by enhancers in existing technologies, but also has a fast onset and high penetration efficiency[1].

HEPES can be found in various skin care products, including GARNIER FLECK ESSENCEN  and ARMANI PRIMA SOFT PEELING LOTION . This may be one of the reasons why such skin care products work so well.

HEPES also has a function of softening and promoting cell regeneration.

HEPES, which belongs to a weak acid system, and is similar to a macromolecular acid. It has the effect of softening keratin and promoting cell metabolism. HEPES is very common in whitening and light spots, anti-decay repair skin care products. Interacting with other ingredients, it can gently remove old keratinocytes, effectively promote the renewal of basal cells, achieve smooth, soft skin and bright skin effect.


HEPES also has synergistic sun protection, strengthening skin barrier and other effects[2].Some products such as KIEHL'S Over-night Biological Peel. are welcomed by people with sensitive skin, because the addition of HEPES improves rough skin texture and reducing pores.

In addition to some of the products mentioned in the article, HEPES is used in many water-based, emulsion creams, and cleansing cosmetics. Hope this article gave you a new understanding of HEPES.


Related Links:HEPES

References:

[1]CN105560077B  Cosmetic penetration enhancer

[2]CN110461317A Skin barrier enhancer, pharmaceutical composition, medicinal cosmetics and cosmetic methods


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