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CAS: 1135-40-6| The application of CAPS in biosensors

2024-01-03

Product NameCAPS

CAS1135-40-6

Molecular Formula C9H19NO3S

Article No.H0014

Structural Formula


Product Introduction

CAPS is a chemical substance that can mainly be used as a biological buffer in biochemical diagnostic kits, DNA/RNA extraction kits, PCR diagnostic kits, and buffer solutions for enzyme chemistry and HPLC separation of alkaline drugs

Application of CAPS

A biosensor is a molecular measurement device that uses molecular recognition elements equipped with detection units for enzymes and other biological substances, as well as transducers such as electrodes. It is used for the determination of various analytical objects in organisms represented by glucose. Biosensors typically have electrodes and a reagent layer loaded on the electrode. As a method for forming a reagent layer, there is a method of coating a reagent solution containing oxidoreductases and electron transfer substances on the electrode and drying it. The uneven concentration or quantity of reagents in the reagent layer is the reason for the uneven dissolution of reagents, which in turn leads to a decrease in reproducibility. Therefore, the CN116930285A patent provides a manufacturing method for biosensors and biosensors. The biosensor consists of three parts: substrate, conductive part, and reagent layer. The reagent layer is composed of oxidoreductases and electron transfer substances, including the reagent layer, buffer, amino acids, surfactants, and binders.

As a buffering agent, it can be phosphate buffering agent, amine buffering agent, and buffering agent with carboxyl groups, etc. Amino buffering agents can be tri (hydroxymethyl) aminomethane, N - (2-acetylamino) -2-aminoethanesulfonic acid, N-cyclohexyl-2-aminoethanesulfonic acid, 3- (cyclohexylamino) -2-hydroxy-1-propanesulfonic acid, N-tri (hydroxymethyl) methyl-3-aminopropane sulfonic acid, CAPS (N-cyclohexyl-3-aminopropane sulfonic acid), bis (2-hydroxyethyl) iminotri (hydroxymethyl) methane)2-hydroxy-N-tris (hydroxymethyl) methyl-3-aminopropane sulfonic acid, N-tri (hydroxymethyl) methyl-2-aminoethanesulfonic acid, N - [tri (hydroxymethyl) methyl] glycine, and ADAN - (2-acetylamino) iminodiacetic acid), etc.

Compared to existing biosensors, the biosensor in this patent has higher reproducibility and measurement accuracy.

 

 

 

References

CN116930285A Manufacturing methods for biosensors and biosensors.

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